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February 1, 2010 - There are large number of studies both in vitro and in vivo that have demonstrated the beneficial effects of diets rich in fruits, vegetables and beverages. These positive effects are attributed in part to Phenolic compounds. Phenolic compounds make up a major portion of compounds in plants, especially in their seeds and green leaves, in an effort to protect them from oxidative damage through their antioxidant activity. Now, its believed that these benefits can be extended to humans as well...
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The biological and health effects of coffee have been widely investigated. Coffee contains a significant amount of antioxidants of the hydrocinnamic acids family: chlorogenic acids (CGA), which includes caffeoylquinic acids (CQA) with the main isomers (3-, 4- and 5-CQA), and related compounds such as caffeic acid, ferulic acid and p-coumaric acid; these compounds are the main of the phenolic fraction occurring in green coffee beans.
Roasting noticeably affects the composition of coffee polyphenols through Maillard reaction, some phenolic compounds can be lost; however, new compounds with antioxidants activity are being developed. Indeed, beans that have been roasted under intermediate conditions (medium-roasted coffee) have maximum antioxidant activity.
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A single cup of coffee may contain 70 – 350 mg of chlorogenic acids. Some studies dealing with antioxidant activity of commonly consumed polyphenolic beverages confirmed that 5-CQA is one of the most active fraction against particular oxidative processes. Moreover, the concept of bioavailability is being applied to phenolics acids, since they are directly absorbed by human body and this is an essential step to understand their health –promoting properties.
Dr. Luz Stella Artajo Medina -
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